Trapping cortical rat neurons


Heida, T. and Rutten, W.L.C. and Marani, E. (2000) Trapping cortical rat neurons. In: 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, July 23-28, 2000, Chicago IL (pp. pp. 1291-1294).

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Abstract:Cortical rat neurons were trapped by dielectrophoresis (DEP). Experimental data were compared with theoretically deduced relationships. The neuron was represented by a single-shell model. A planar quadrupole electrode structure was used for the creation of a nonuniform field. The electrode structure was modeled as four point charges. The experimental data did almost completely fit the theoretical yield/time relationship. The theoretical yield/amplitude relationship, however, did only apply for a restricted amount of frequencies. The experimental frequency behaviour (i.e., the DEP-spectrum) did not apply to the theory. A difference in neuronal physiological state can produce different DEP-spectra. For two frequencies (10 kHz and 14 MHz) adhesion to the substrate and outgrowth of the neurons was investigated
Item Type:Conference or Workshop Item
Copyright:©2000 IEEE
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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