Procedures for the selective alkylation of calix[6]arenes at the lower rim

Share/Save/Bookmark

Janssen, Rob G. and Verboom, Willem and Reinhoudt, David N. and Casnati, Alessandro and Freriks, Margret and Pochini, Andrea and Ugozzoli, Franco and Ungaro, Rocco and Nieto, Pedro M. and Carramolino, Mar and Cuevas, Felix and Prados, Pilar and Mendoza de, Javier (1993) Procedures for the selective alkylation of calix[6]arenes at the lower rim. Synthesis, 1993 (4). pp. 380-386. ISSN 0039-7881

[img]
Preview
PDF
686Kb
Abstract:New partially alkylated calix[6]arenes have been synthesized. Depending on the conditions, mono-, 1,2-di-, 1,3-di, 1,2,3-tri-, 1,3,5-tri-, 1,2,4,5-tetra-, and 1,2,3,4,5-pentamethylated derivatives of p-tert-butylcalix[6]arene could be obtained in moderate to good yields. Methylation or benzylation of the parent calix[6]arene showed a regioselectivity towards 1,2-di-, and 1,2,3-trisubstitution. The solid state structure of 1,2,4,5-tetrasubstituted p-tert-butylcalix[6]arene [R=O(CH2CH2O)2CH3] has been elucidated by X-ray analysis.


Item Type:Article
Copyright:© Georg Thieme Verlag 1993
Faculty:
Science and Technology (TNW)
Research Group:
Link to this item:http://purl.utwente.nl/publications/12578
Official URL:http://dx.doi.org/10.1055/s-1993-25868
Export this item as:BibTeX
EndNote
HTML Citation
Reference Manager

 

Repository Staff Only: item control page

Metis ID: 106759