Complexation of neutral molecules by synthetic hosts

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Reinhoudt, David N. and Veggel, Frank C.J.M. van (1993) Complexation of neutral molecules by synthetic hosts. Pure and Applied Chemistry, 65 (5). pp. 965-969. ISSN 0033-4545

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Abstract:The interactions of neutral polar molecules with synthetic (macrocyclic) hosts are described. Extraction, NMR spectroscopy, polarography, and membrane transport studies have been carried out in order to understand these interactions. A step-wise process is described in which ultimately a general approach for a rational design of hosts is obtained. This approach has finally led to the first transfer of urea across a membrane by a neutral host (carrier) in which binding sites are placed in such a way that all possible interactions with urea are indeed used.
Item Type:Article
Additional information:12th IUPAC Conference on Chemical Thermodynamics, Snowbird, Utah, USA, 16–21 August 1992
Copyright:© 1993 IUPAC
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Link to this item:http://purl.utwente.nl/publications/12280
Official URL:http://dx.doi.org/10.1351/pac199365050965
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Metis ID: 106584